Hepatitis induced by nomifensine.
نویسندگان
چکیده
1 Soules MR, McCarty KS. Leiomyomas: steroid receptor content. Am J Obstet Gynecol 1982;143:6-11. 2 Fraser HM. New prospects for luteinising hormone releasing hormone as a contraceptive and therapeutic agent. Br MedJe 1982;285:990-1. 3 Sutherland IA, White S, Chambers GR, et al. A miniature infuser for the pulsatile administration of LHRH. J Biomed Eng 1984;6:129-33. 4 Chong AP, Baggish MS. Management of pelvic endometriosis by means of intraabdominal carbon dioxide laser. Fertil Steril 1984;41:14-9. 5 Fillicori M, Hall DA, Loughlin JS, Rivier J, Vale W, Crowley WF. A conservative approach to the management of uterine leiomyome. Pituitary desensitization by a luteinizing hormone releasing hormone analogue. Am J Obstet Gynecol 1983; 147:726-7.
منابع مشابه
Effect of nomifensine on anacoccygeus contraction induced by noradrenaline and electrical stimulation
Nomifensine, an antidepressant agent, competitively inhibits dopamine uptake in the caudate-putamen and nucleus accumbens and binds to both dopaminergic and noradrenergic reuptake sites in the striatum and thalamus. In this study the effect of nomifensine on anacoccygeus contraction induced by noradrenaline and electrical stimulation was investigated in rats and compared to the effect of phen...
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Nomifensine (Mental. Alival; Hoechst. Frankfurt. FRG). an antidepressant drug. may cause immune hemolytic anemia (IHA) of the so-called immune complex type that is believed to occur by means of an innocent-bystander mechanism. In this report we describe findings that are not consistent with this mechanism in a patient with nomifensine-induced intravascular IHA associated with renal failure. In ...
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A patient with drug induced alveolitis due to an antidepressant drug, nomifensine, is described. After an inadvertent rechallenge by the patient sequential bronchoalveolar lavage was carried out. Twenty four hours after the rechallenge the lavage fluid contained a high cell count with neutrophils predominating. Seven days after challenge the cells were predominantly lymphocytes.
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The mechanisms of dopamine (DA) release central nerve endings have been investigated utilizing superfused rat striatal synaptosomes. Nomifensine was selected as a tool to discriminate between release mediated by the DA carrier and release occurring independently of the carrier. The following conclusions can be drawn from the results obtained: 1) Alterations of the sodium gradient across the syn...
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Nomifensine is an antidepressant agent that was removed from use because of a high incidence of hemolytic anemia. It contains an N-methyl-8-aminotetrahydroisoquinoline ring which has the potential to be oxidized to quaternary dihydroisoquinolinium and isoquinolinium ions, albeit such a transformation had not been previously observed. In this report, we demonstrate the conversion of nomifensine ...
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عنوان ژورنال:
- British medical journal
دوره 289 6454 شماره
صفحات -
تاریخ انتشار 1984